Metabolites

Secondary Metabolites

What if any plant-based secondary metabolite was accessible in a sustainable, industrially scalable production platform?

Facts

  • Microalgae are micro-organisms with the closest biochemical connection to higher plants;
  • Over the past 25 years, greater than 70% of new pharmaceuticals have come from the natural world – with many coming from higher plants;
  • Similarly, the demand for natural product-based bioactives for biopesticides is growing rapidly;
  • A significant number of plant-based bioactives cannot be chemically synthesized due to their complex structures;
  • The development rate for new, plant-based bioactives would be accelerated if sustainable production/manufacturing was not an issue;

    Algenious secondary metabolites – accessible, sustainable, plant bioactives

    • Suite of vectors and strains with options for nuclear or chloroplast expression as well as pathway  creation/re-creation;
    • Choice of several proven, industrially scalable microalgal chassis hosts;
    • Potential for combination with insertional mutagenesis platform for additional refinement of strains;
    • Core R&D program with proven application for higher plant secondary metabolite production; Ongoing collaborative research within the TriForC FP7 project - towards sustainable, combinatorial production of triterpenoids in microalgal production hosts;
    • Strain engineering platform supported by algal cultivation facilities and transcriptomic and biochemical analyses suites.

     Begin the conversation

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