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By algenuity 21 Dec, 2017
Welcome to the December edition of our quarterly Algenuity newsletter!

We hope this newsletter will help you make the most of your Algem labscale photobioreactor, keep you updated on the latest Algenuity news and partnership opportunities, and also show you some interesting algal research examples from our lab and around the world.

Merry Christmas and Happy Holidays! : )
By algenuity 20 Dec, 2017

Algenuity is a globally recognised, UK-based algal biotechnology company that currently operates as a wholly-owned division of Spicer Consulting Limited, a UK-based OEM of specialised electronics. Algenuity operates within a technology development and licensing model, developing solutions to deliver to the algal biomass and bioproducts industry to drive economics, fuel industry expansion, and identify and exploit new opportunities. Our vision is to be the leading global algal biotechnology company and our mantra is simple, " Making Algae Work ".


We are seeking a talented individual to fill the role of Technical Sales and Product Support within our commercial Algem photobioreactor products team.


The primary role for the successful individual will be to take on responsibility for our Algem family of specialised photobioreactors, through fielding customer enquiries and development of sales leads to installation, training and after-sales support. This will include travel to customer sites within the UK, Europe and Asia as well as working closely with our dedicated and experienced US agent. To support the product sales you will prepare marketing and conference materials, and develop applied case-studies of experimental data based upon your own use of the Algem photobioreactor family of products. You will have freedom to develop strategy around connecting our business opportunity with customer needs. You will be encouraged to present the Algem at UK and international conferences and trade shows to both academic and commercial customers. In addition, you will be encouraged to learn about all aspects of Algem family product manufacture and support services, liaising with relevant departments within the company. There will be an opportunity to grow into the role of Product Manager as well as contributing to the development of the Algenuity commercial strategy.


Position requirements:

  • A strong degree in biological sciences (B.Sc. minimum, M.Sc. preferred)
  • 2 years demonstrated minimum experience in sales/customer support for analytical scientific instruments;
  • Strong practical abilities including ability to problem solve and think actively at customer sites;
  • Outstanding communication skills both written and oral, including the presentation of scientific information to individual customers and at scientific meetings, as well as performing on-site customer demonstrations and training;
  • Strong computing skills including use of spreadsheets, presentation software and data analysis software
  • Fluent in English (written and spoken);
  • Ability to work within a team as well as to work independently on specific projects;
  • Ability to work to deadlines as well as to project deliverables;
  • Eligibility to live and work in the United Kingdom;
  • Ability to obtain a valid passport.

Desired (but not necessary):
  • Working practical knowledge of microalgal cultivation;
  • Bi or multi-lingual;
  • Electronics and/or mechanical assembly experience.

This is a full-time position, working at our dedicated site in Bedfordshire, within the United Kingdom’s Golden Triangle for Biotech. Our site benefits from easy access to Central London, Cambridge, and London Luton airport.

We are offering a competitive salary commensurate with experience, and a generous company pension contribution, with the opportunity for performance-related bonus along with discretionary profit-sharing. Applicants should submit a Curriculum Vitae and cover letter to jcp@algenuity.com by 19 January 2018.

  NOTE – you will not be considered for this position unless you are eligible to work in the UK.

By algenuity 20 Dec, 2017

Algenuity (a Division of Spicer Consulting Ltd) is the UK’s leading algal biotechnology company. We develop breakthrough technologies for the rapidly expanding algal biomass and bioproducts industry. Our vision is to build our business into a leading global technology company and our mantra is simple – “ Making Algae Work ”.

We are currently seeking an exceptional talent to join our leadership team as the business enters an exciting period of growth. You will work closely with the CEO and Commercial Development Group to help steer the Company through this pivotal phase. You will ensure that the Company’s technical resources and capabilities are matched to deliver against its corporate goals and vision.

You will lead the current internal and external R&D activities, and you will be responsible for recruiting and training new staff. The successful candidate will combine technical excellence with strategic insight to ensure Algenuity retains and builds upon its competitive advantage. Innovation is at the heart of this appointment, and you will liaise closely with key academics and industry leaders to map the technology landscape, understand sector challenges and develop commercially attractive solutions.

The successful candidate will meet the following requirements:

  • A PhD in life sciences with a minimum 5 years post-doctoral experience
     AND
  • A minimum 3 years relevant industry experience including successful writing of grants and/or collaborative R&D proposals and a proven track record of management of projects to successful outcomes;
  • A background in biochemistry/biotechnology/molecular biology/synthetic biology;
  • A demonstrated innovator with ability to synthesise and develop complex ideas for problem-solving and technology development – combining technical excellence with strategic insight;
  • Outstanding interpersonal skills with significant leadership experience – and a proven ability to lead and inspire cross-disciplinary teams;
  • Excellent organisational, communication, problem solving and presentation skills;
  • Charismatic and compelling in front of a variety of audiences - ability to represent the company at technical meetings and other external events;
  • Fluent in English – spoken and written;
  • Available to start April 2018;
  • Eligible to live and work in the United Kingdom.

This is a full-time position, working at our dedicated site in Bedfordshire, within the United Kingdom’s Golden Triangle for Biotech. Our site benefits from easy access to Central London, Cambridge, and London Luton airport.

We are offering a competitive salary commensurate with experience, and a generous company pension contribution, with the opportunity for performance-related bonus along with discretionary profit-sharing. Applicants should submit a Curriculum Vitae and cover letter to jcp@algenuity.com by 19 January 2018.

  NOTE – you will not be considered for this position unless you are eligible to work in the UK.

By algenuity 14 Dec, 2017

Mike Yates recently caught up with Dr. Yanan Xu, a Postdoctoral Research Fellow in Pat Harvey's algal research lab at the University of Greenwich.


Thank you for taking time to do this interview.  Please tell us a little bit about yourself and where you work.


My name is Yanan Xu, and I am a Postdoctoral Research Fellow in Pat Harvey ’s algal research group at the University of Greenwich. It is part of the Faculty of Engineering and Science.


How long have you been an Algem User?


I have been using the Algem since December 2012. I used one of the initial beta versions of the Algem while I was doing my PhD in Saul Purton’s lab at University College London (UCL). I then continued to use the Algem shortly after I joined Pat Harvey’s lab in February 2014.


Wow, you are one of the original beta-testers of the Algem! That is almost 5 years of Algem use – that’s brilliant. What species or samples do you work with?


It varies depending on the research. In the past, I worked a lot with Chlorella strains, but I have now been working on different strains of Dunaliella and Haematococcus .


What is briefly the aim of your research?


The aim of our research is to characterise isolated algal strains and evaluate the potential for high value products.


Interesting. What do you use the Algem for?


Our lab has three Algem systems (the equivalent of six reactor vessels), and I use the Algems to compare different algal strains under a range of environmental conditions such as light, temperature, pH, and salinity.


You published a paper last year using Algem, and you have another paper using Algem that has been submitted?


Yes, last year in May 2016, we published a paper using the Algem in Plant Physiology and Biochemistry titled, “ The influence of photoperiod and light intensity on the growth and photosynthesis of Dunaliella salina (chlorophyta) CCAP 19/30 ”.  We have submitted a paper this year that is forthcoming titled, “ Potential of new isolates of Dunaliella salina for natural β-carotene production ‚Äč”.


That’s exciting – I look forward to reading it. What do you like about the Algem?


I like that the Algem results are highly reproducible. I can set up multiple algal cultures with exactly the same conditions, and I can also precisely control the conditions of CO2, pH, light intensity, and temperature.

Do you use any other growing systems other than the Algem and how did they compare?


We use incubators and growth cabinets for flask cultures, and they are good for setting up large amounts of cultures. However, the conditions of each culture may vary a lot depending on the position of the flask in each of those set ups.


Is there one thing you would recommend other Algem users to try?


I like the Algem software and how it can be easily customised. For example, Dunaliella salina does not have a cell wall, and it is very fragile and does not like being mixed all the time. The Algem software allows you to easily customise the mixing so that it briefly mixes before an optical density (OD) measurement. This is very useful.

Now to end with a fun question - what is your favourite alga and why?


I have to say Dunaliella salina . I have spent the most time researching Dunaliella salina compared to any other strain – I have been researching it for almost 4 years now. There is just so much to explore about this strain.


I have a soft spot for Dunaliella salina too. Thank you for your time, Yanan. It has been great to speak with you.

You can learn more about the Algem labscale photobioreactor here  on our website and get in touch with us to talk here .

By algenuity 06 Nov, 2017

Algenuity was part of a four-year EU funded project with 11 partners called TriForC that officially ended last week on 31st October 2017. Mike Yates caught up with Dr. Sarah D’Adamo, Algenuity’s Lead Scientist, to learn more about TriForC and some of the concluding outcomes.


Starting from the beginning, what does TriForC stand for and what was the goal of the project?

TriForC stands for “ Tri terpenes for C ommercialisation”. The goal was to create a pipeline and platform to discover, sustainably produce, and commercialise known and novel high-value triterpenes. Several chassis platforms were explored: microalgae, yeast, and tobacco. Algenuity led the microalgal expression platform work.

What are triterpenes and why are triterpenes important?

Triterpenes are secondary metabolites that are often found in plants, and plants uses them as natural self-defence mechanisms from pests.

Plant triterpenes have been studied as novel bio-pesticides in the agri-tech space or unique anti-inflammatory agents in the pharmaceutical space. If you do a search on the US clinical trials database or a patent search under specific triterpenes, you will find several drugs that are in clinical trials and that use triterpenes as an active pharmaceutical ingredient (API). There is a lot of potential for these natural solutions.

Why would you need a platform like microalgae, yeast, or tobacco to express triterpenes?

One of the challenges is that certain triterpenes are structurally complex and are difficult to create via chemical synthesis.

Triterpenes are often found as complex mixtures in their natural hosts of plants, and the desired triterpene is usually only present in small amounts. This makes the isolation and large-scale extraction very costly.  

One would think – why not increase the yields of triterpenes in the natural host of plants and use plants as the platform? The problem is that most plants do not have an established transformation procedure, and it is difficult to scale up and grow plants on a suitable commercial scale. Furthermore, there are sustainability and possible ethical concerns of cutting down trees and plants to source a chemical.

An industrial biotech platform based on microalgae would provide a consistent, continuous (not limited to harvests), sustainable, and homogenous supply.

Was the team successful in producing triterpenes in microalgae? And if so, what microalgal strain?

Yes! We successfully expressed selected triterpenes in the diatom and brown microalga, Phaeodactylum tricornutum . However, the triterpene yields were still low and more work needs to be done to optimise the pathway in order to go towards industrial scale. We did, however, accomplish our deliverable targets of triterpene expression in microalgae.

Oh brilliant. Did you try any other microalgal species?

Yes, we tried Chlamydomonas reinhardtii and Nannochloropsis oceanica , but we were unsuccessful with those strains. We stopped work on Chlamydomonas early on. Nanno and Phaeo were the two main work horse strains for the project.

By algenuity 27 Sep, 2017
Algae Industry Magazine posted an article titled, "Algenuity takes quality control testing to the next level" yesterday Tuesday 26th September 2017.  

The article highlights the rigorous quality control testing process for the Algem labscale photobioreactor and Algenuity's commitment to precision lighting and temperature control for highly accurate and reproducible data.

The article can be found at  http://www.algaeindustrymagazine.com/algenuitys-algem-photobioreactor-system/
By algenuity 25 Sep, 2017
Welcome to the September edition of our quarterly Algenuity newsletter!

We hope this newsletter will help you make the most of your Algem labscale photobioreactor, keep you updated on the latest Algenuity news and partnership opportunities, and also show you some interesting algal research examples from our lab and around the world.
By algenuity 19 Sep, 2017

Our Algenuity team contacted an Algem user, Victor Sanchez, a PhD student at UCL, to ask him about his experience with the Algem labscale photobioreactor.  Below is a short interview.


Where do you work?

 

In the Biochemical Engineering Department at University College London.

 

How long have you been an Algem User?

 

Algem user since September 2016. 10 months.

 

What species or samples do you work with?

 

Chlamydomonas reinhardtii .

 

What is briefly the aim of your research?

 

Characterising the effects growing under different wavelengths has on C. reinhardtii at the physiological, metabolic and genetic levels.

 

What do you use the Algem for?

 

Growing batch cultures at different wavelengths with pH control.

 

What do you like about the Algem?


  • Its reproducibility.
  • The ability of controlling pH in flask cultures.
  • The ability to take samples maintaining axenic conditions without disturbing culture conditions.
  • The tight specs of the lights.

Did you use any other growing systems before the Algem and how did they compare?

 

To grow cells under different wavelengths I “engineered” my own light panel with RGBW LED strips. However the light distribution was not uniform (presumably my lack of electrical engineering skills did not help either). Therefore, performing experiments in triplicate and getting robust and consistent results was very hard. The Algem allows a standardisation and a high degree of control over culture conditions, which translates to high reproducibility of results.


Is there one thing you would recommend other Algem users to try?


The aseptic sampling with the three-way valve makes life so much easier. Especially if like me, the nearest safety cabinet to your Algem is relatively far away.

 

Learn more about the ascetic sampling technique in our application note: https://www.algenuity.com/algem-aseptic-real-time-sampling-protocol . Email info@algenuity.com for more information.

By algenuity 20 Jun, 2017
Welcome to our first Algenuity newsletter!  We hope this newsletter will help you make the most of your Algem labscale photobioreactor, keep you updated on the latest Algenuity news and partnership opportunities, and also show you some interesting algal research examples from our lab and around the world.
By algenuity 10 May, 2017

Arthrospira platensis (commonly referred to as Spirulina , despite belonging to a morphologically distinct genus) is a filamentous cyanobacterium characterised by its beneficial nutritional content, left handed open helical form, and ability to grow under highly alkaline conditions. A. platensis is protein rich and has been utilised as a traditional foodstuff in multiple cultures, most notably in Central America and in the region surrounding Lake Chad. Recently A. platensis has experienced a resurgence as a health food and a source of the blue pigment phycocyanin for use as a food colourant.

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By algenuity 21 Dec, 2017
Welcome to the December edition of our quarterly Algenuity newsletter!

We hope this newsletter will help you make the most of your Algem labscale photobioreactor, keep you updated on the latest Algenuity news and partnership opportunities, and also show you some interesting algal research examples from our lab and around the world.

Merry Christmas and Happy Holidays! : )
By algenuity 20 Dec, 2017

Algenuity is a globally recognised, UK-based algal biotechnology company that currently operates as a wholly-owned division of Spicer Consulting Limited, a UK-based OEM of specialised electronics. Algenuity operates within a technology development and licensing model, developing solutions to deliver to the algal biomass and bioproducts industry to drive economics, fuel industry expansion, and identify and exploit new opportunities. Our vision is to be the leading global algal biotechnology company and our mantra is simple, " Making Algae Work ".


We are seeking a talented individual to fill the role of Technical Sales and Product Support within our commercial Algem photobioreactor products team.


The primary role for the successful individual will be to take on responsibility for our Algem family of specialised photobioreactors, through fielding customer enquiries and development of sales leads to installation, training and after-sales support. This will include travel to customer sites within the UK, Europe and Asia as well as working closely with our dedicated and experienced US agent. To support the product sales you will prepare marketing and conference materials, and develop applied case-studies of experimental data based upon your own use of the Algem photobioreactor family of products. You will have freedom to develop strategy around connecting our business opportunity with customer needs. You will be encouraged to present the Algem at UK and international conferences and trade shows to both academic and commercial customers. In addition, you will be encouraged to learn about all aspects of Algem family product manufacture and support services, liaising with relevant departments within the company. There will be an opportunity to grow into the role of Product Manager as well as contributing to the development of the Algenuity commercial strategy.


Position requirements:

  • A strong degree in biological sciences (B.Sc. minimum, M.Sc. preferred)
  • 2 years demonstrated minimum experience in sales/customer support for analytical scientific instruments;
  • Strong practical abilities including ability to problem solve and think actively at customer sites;
  • Outstanding communication skills both written and oral, including the presentation of scientific information to individual customers and at scientific meetings, as well as performing on-site customer demonstrations and training;
  • Strong computing skills including use of spreadsheets, presentation software and data analysis software
  • Fluent in English (written and spoken);
  • Ability to work within a team as well as to work independently on specific projects;
  • Ability to work to deadlines as well as to project deliverables;
  • Eligibility to live and work in the United Kingdom;
  • Ability to obtain a valid passport.

Desired (but not necessary):
  • Working practical knowledge of microalgal cultivation;
  • Bi or multi-lingual;
  • Electronics and/or mechanical assembly experience.

This is a full-time position, working at our dedicated site in Bedfordshire, within the United Kingdom’s Golden Triangle for Biotech. Our site benefits from easy access to Central London, Cambridge, and London Luton airport.

We are offering a competitive salary commensurate with experience, and a generous company pension contribution, with the opportunity for performance-related bonus along with discretionary profit-sharing. Applicants should submit a Curriculum Vitae and cover letter to jcp@algenuity.com by 19 January 2018.

  NOTE – you will not be considered for this position unless you are eligible to work in the UK.

By algenuity 20 Dec, 2017

Algenuity (a Division of Spicer Consulting Ltd) is the UK’s leading algal biotechnology company. We develop breakthrough technologies for the rapidly expanding algal biomass and bioproducts industry. Our vision is to build our business into a leading global technology company and our mantra is simple – “ Making Algae Work ”.

We are currently seeking an exceptional talent to join our leadership team as the business enters an exciting period of growth. You will work closely with the CEO and Commercial Development Group to help steer the Company through this pivotal phase. You will ensure that the Company’s technical resources and capabilities are matched to deliver against its corporate goals and vision.

You will lead the current internal and external R&D activities, and you will be responsible for recruiting and training new staff. The successful candidate will combine technical excellence with strategic insight to ensure Algenuity retains and builds upon its competitive advantage. Innovation is at the heart of this appointment, and you will liaise closely with key academics and industry leaders to map the technology landscape, understand sector challenges and develop commercially attractive solutions.

The successful candidate will meet the following requirements:

  • A PhD in life sciences with a minimum 5 years post-doctoral experience
     AND
  • A minimum 3 years relevant industry experience including successful writing of grants and/or collaborative R&D proposals and a proven track record of management of projects to successful outcomes;
  • A background in biochemistry/biotechnology/molecular biology/synthetic biology;
  • A demonstrated innovator with ability to synthesise and develop complex ideas for problem-solving and technology development – combining technical excellence with strategic insight;
  • Outstanding interpersonal skills with significant leadership experience – and a proven ability to lead and inspire cross-disciplinary teams;
  • Excellent organisational, communication, problem solving and presentation skills;
  • Charismatic and compelling in front of a variety of audiences - ability to represent the company at technical meetings and other external events;
  • Fluent in English – spoken and written;
  • Available to start April 2018;
  • Eligible to live and work in the United Kingdom.

This is a full-time position, working at our dedicated site in Bedfordshire, within the United Kingdom’s Golden Triangle for Biotech. Our site benefits from easy access to Central London, Cambridge, and London Luton airport.

We are offering a competitive salary commensurate with experience, and a generous company pension contribution, with the opportunity for performance-related bonus along with discretionary profit-sharing. Applicants should submit a Curriculum Vitae and cover letter to jcp@algenuity.com by 19 January 2018.

  NOTE – you will not be considered for this position unless you are eligible to work in the UK.

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